Sunday 2 June 2019

precision medicine in cancer care



The  new paradigm in cancer management – precision medicine

A form of medicine that uses information about a person’s genes and proteins to prevent, diagnose, and treat disease.

Most standard chemo drugs work by killing cells in the body that grow and divide quickly. Cancer cells divide quickly, which is why these drugs often work against them. But chemo drugs can also affect other cells in the body that divide quickly, which can sometimes lead to serious adverse effects

With the advancement of scince a lot of information has been gathered regarding the genes and proteins that cause the formation, growth and spread of cancer cells.

This new information is now being utilized to specifically design drugs that target these genes and proteins

There are many different types of cancer, and not all cancer cells are the same. For example, colon cancer and breast cancer cells often have different gene changes that help them grow and/or spread. Even among people with colon cancer, the cancer cells can have different gene changes.

Therefore for each patient a portion of the tumor tissue is taken and subjected to molecular and genetic analysis and depending on the target identified specific drugs are administered to counter their effects – hence the name ‘precision medicine’

How it works –

  • Block or turn off chemical signals that tell the cancer cell to grow and divide
  • Change proteins within the cancer cells so the cells die
  • Stop making new blood vessels to feed the cancer cells
  • Trigger your immune system to kill the cancer cells
  • Carry toxins to the cancer cells to kill them, but not normal cells





More effective with better side effect profile. May be administered in outpatient setting. Better quality of life

Before 2001, fewer than 1 in 3 people with chronic myelogenous leukemia (CML) survived more than five years after diagnosis. Then, along came Gleevec. The U.S. Food and Drug Administration (FDA) approved the drug as a targeted treatment for CML in 2001. Treatment for CML hasn’t been the same since. A 10-year follow-up study showed that 83 percent of people using the drug survived 10 years, some well beyond the decade mark. They did so without unacceptable toxic effects.

Long-term results from a major international clinical trial reveal that a fifth of patients with advanced gastrointestinal stromal tumours (GIST) continue to survive a decade after first taking the targeted drug imatinib, also known as Glivec.

Some 10% of patients are still on the trial after 10 years, living free of any progression of their cancer – providing evidence that targeted cancer therapy can deliver dramatic, long-term responses even in patients with advanced cancer that has spread round the body.




Dr VIBHOR MAHENDRU

Sr Consultant – Cancer Surgery

Sahara hospital

SM Cancer Centre

A26, Faizabad road

Indiranagar

3 comments:

  1. My name is hoover, my 18 year old daughter, Tricia was diagnosed with herpes 3 years ago. Since then, we have moved from one hospital to another. We tried all kinds of pills, but every effort to get rid of the virus was futile. The bubbles continued to reappear after a few months. My daughter was using 200mg acyclovir pills. 2 tablets every 6 hours and 15g of fusitin cream. and H5 POT. Permanganate with water to be applied twice a day, but all still do not show results. So, I was on the internet a few months ago, to look for other ways to save my only son. Only then did I come across a comment about the herbal treatment of Dr Imoloa and decided to give it a try. I contacted him and he prepared some herbs and sent them, along with guidance on how to use them via the DHL courier service. my daughter used it as directed by dr imoloa and in less than 14 days, my daughter recovered her health. You should contact dr imoloa today directly at his email address for any type of health problem; lupus disease, mouth ulcer, mouth cancer, body pain, fever, hepatitis ABC, syphilis, diarrhea, HIV / AIDS, Huntington's disease, back acne, chronic kidney failure, addison's disease, chronic pain, Crohn's pain, cystic fibrosis, fibromyalgia, inflammatory Bowel disease, fungal nail disease, Lyme disease, Celia disease, Lymphoma, Major depression, Malignant melanoma, Mania, Melorheostosis, Meniere's disease, Mucopolysaccharidosis, Multiple sclerosis, Muscular dystrophy, Rheumatoid arthritis Alzheimer's disease, parkinson's disease, vaginal cancer, epilepsy Anxiety Disorders, Autoimmune Disease, Back Pain, Back Sprain, Bipolar Disorder, Brain Tumor, Malignant, Bruxism, Bulimia, Cervical Disc Disease, Cardiovascular Disease, Neoplasms , chronic respiratory disease, mental and behavioral disorder, Cystic Fibrosis, Hypertension, Diabetes, Asthma, Autoimmune inflammatory media arthritis ed. chronic kidney disease, inflammatory joint disease, impotence, alcohol spectrum feta, dysthymic disorder, eczema, tuberculosis, chronic fatigue syndrome, constipation, inflammatory bowel disease. and many more; contact him at drimolaherbalmademedicine@gmail.com./ also with whatssap- + 2347081986098.

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  3. I also have a long story, but long story short i had a pain on my left side after a bout of diarrhea which i thought was because i got sick with Covid. but after I recovered from my diarrhea after drinking Dr Itua herbal medicine which He prepared then sent it to me through courier service and he instructed me on how to drink it to cure it. When the pain hit i went to the hospital, luckily i'm active duty military so they took me in at the ER. Once in there. They did an IMMEDIATE CT. Within 2 hours a GI surgeon showed up in my ER room and said we need to do surgery like yesterday on you. Doesn't matter what that is in your gut it needs to come out because it's causing about an 80% blockage. The next day a colonoscopy confirmed cancer. Next day after that I had surgery to remove half a foot of colon but it didn't go that way because Dr Itua assure me that his herbal medicine will makes me well and honestly Dr Itua herbal medicine really help me and today I'm cured and healthy through Dr Itua herbal center
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